A Research Paper Published in Nucleic...

Researchers from the Department of Chemistry, Branimir Bertoša and Zoe Jelić Matošević, in collaboration with reserchers from the Austrian Institute of Technology in Vienna (Ivan Barišić, David Kuťák, Lucas Melo, Fabian Schroeder, Natalie Mutter) have published the scientific publication CATANA: an online modelling environment for proteins and nucleic acid nanostructures. The paper was published in the prestigious journal Nucleic Acids Research (IF = 16.971).

The paper presents Catana, a new program for molecular modelling of large biochemical systems. The publication is a result of the joint research in the frame of the EU Horizon 2020 Marilia project, which is partly being conducted at the Chemistry Department of the Faculty of Science. The aim of the project is to develop new assays for the detection of pathogens in water based on protein-protein and protein-DNA interactions. Since modelling of such systems can be very demanding, a novel software, Catana, was developed. Catana provides user friendly interface that enables in silico construction and visualization of such systems, as well as their preparation for computational simulations. Catana was tested on multiple systems, ranging from a small DNA fragement to a large fusion protein, protein-DNA complexes and DNA-origami structures.

Author: Adriana Kenđel
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