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Microbiology of Pathogens

Code: 60241
ECTS: 6.0
Lecturers in charge: izv. prof. dr. sc. Silvija Černi
Lecturers: izv. prof. dr. sc. Silvija Černi - Seminar

izv. prof. dr. sc. Silvija Černi - Practicum
dr. sc. Ivana Grgić - Practicum
dr. sc. Jelena Ivančić Jelečki - Practicum
izv. prof. dr. sc. Snježana Židovec Lepej - Practicum

izv. prof. dr. sc. Marin Ježić - Lectures
izv. prof. dr. sc. Snježana Židovec Lepej - Lectures
Take exam: Studomat
English level:


The lecturer is not able to offer courses in English at this time.

1. komponenta

Lecture typeTotal
Lectures 30
Practicum 15
Seminar 15
* Load is given in academic hour (1 academic hour = 45 minutes)
The course content:
The course introduces the etiological agents of infectious diseases and mechanisms of pathogenesis and prevention thereof

Learning outcomes:
- After completion of lectures and seminars and exercises in course Microbiology of pathogens student will be able to:
- Connect the etiological cause of infectious disease
- To understand mechanisms of microbial pathogenesis
- Know the procedures for prevention of infectious diseases using antigens by vaccinaiton programme
to understan the microbiocentric approach in the pathogenesis of the infectioouse diseases
- Know the basics of biology, transmission and virulence of the most important causes of infective diseases
- Know how to identify medically important microbes and how to determine antibiotic susceptibility

Thematic units of lectures:
1. Introductory lecture, introduction to the organization of the course (the rights and obligations of student)
2. From the theory of miasms to the etiological cause - 1st Part (plague of the 14th century as an example of the epidemic)
3. From the theory of miasms to the etiological cause - Part 2 (history, millestones, scientific approach as a paradigm)
4. Arheae, procariae and eucariae and infectious diseases
5. Terms in microbial pathogenesis, disease as a function of dynamic variables of host and microbes, systemic view on the disease
6. Epidemiological measures: Vograliks chain, prevention of infection
7. Measures of protection against infection. Part 1: active and passive immunization
8. Measures of protection against infection. Part 2: disinfectants and antiseptics, sterilization, causal medication
9. -14. The causes of disease - bacterial, fungal, viral and parasitic etiology: alimentary toxiinfections, poisoning, infections of the upper and lower respirstory system, infections of genito-urinary system, skin infections, infections of the CNS and others.
15. Human mcirobiome: Organization of epidemiology in the Croatia / EU, ECDC, EMA

Seminal topics:
1. Intracellular pathogens
2. Vectors of infectiouse diseases
3. Microbial pathogenesis of plague, Y. pestis
4. Modulation of skin microbiome
5. Differences archaea-prokariae, exo-Earth biology
6. Modulation of virulence of Candida albicans - a model for research

1. Microbiological control of air quality
2. Urine culture, identification of bacteria and antibiogram
3. stool examination on parasites
4. stool examination on salmonella
5. Identification of medically important yeasts, molds and dermatophytes
6. Wound swab on anaerobes, cultivation and identification (api)
7. trichina and artificial digestion
8. Microbiological testing of non-living environment on S. aureus, coliforms
9. Throat swab on BHSA
  1. Kalenić S i sur., Medicinska mikrobiologija, Medicinska naklada, Zagreb, 2014
  2. Kosalec I, Mikrobiologija patogena-seminari, Farmaceutsko-biokmeijski fakultet Sveučilišta u Zagrebu, Zagreb, 2015, u izradi
  3. Cvetnić Z, Kosalec I, Praktikum : odabrana poglavlja mikrobiologije s parazitologijom, Farmaceutsko-biokemijski fakultet Sveučilišta u Zagrebu, Zagreb, 2005, ISBN: 953-6256-46-0
  4. Ropac D i sur, Epidemiologija zaraznih bolesti, Medicinska naklada, Zagreb, 2003
  5. Casadevall A, Pirofski L, Host-pathogen interactions: redefining the basic concepts of virulence and pathogenicity. Infect Immun 1999; 67:3703-13.
  6. Casadevall A, Pirofski L, Host-pathogen interactions: the attributes of virulence. J Infect Dis 2001; 184:337-44.
  7. Brogden K. A. i drugi (Ur.), Virulence mechanisms of bacterial pathogens, 3rd Ed., AS, Press, Washington, 2000.
3. semester
Izborni predmeti - Regular module - Physiology and Immunobiology
Consultations schedule: