Project UKF 1B, 10/07

Macromolecular complexes of aminoacyl-tRNA synthetases and their role in translational quality control and non-ribosomal peptide synthesis


Publication list:

  1. Bilokapic, S., Rokov Plavec, J., Ban, N. and Weygand-Durasevic, I. (2008) Structural flexibility of the methanogenic-type seryl-tRNA synthetase active site and its implication for specific substrate recognition, FEBS J. 275, 2831-2844.
  2. Bilokapic, S., Ivic, N, Godinic Mikulcic, V., Piantanida, I., Ban, N. and Weygand-Durasevic, I. (2009) Idiosyncratic helix-turn-helix motif in Methanosarcina barkeri seryl-tRNA synthetase has a critical architectural role, J. Biol. Chem. 284, 10706-10713.
  3. Lesjak, S. and Weygand-Durasevic, I. (2009) Recognition between tRNASer and archaeal seryl-tRNA synthetases monitored by suppression of bacterial amber mutations, FEMS Lett. 294, 11-118.
  4. Bilokapic, S., Ban, N., and Weygand-Durasevic, I. (2009). Seryl-tRNA synthetases: enzymes with multiple personalities, Croatica Chem. Acta 82, 51-59.
  5. Jaric, J., Bilokapic, S., Lesjak, S., Crnkovic, A., Ban, N., and Weygand-Durasevic, I. (2009) Identification of amino acids in the N-terminal domain of atypical methanogenic-type seryl-tRNA synthetase critical for tRNA recognition, J. Biol. Chem. 284, 30643-30651.
  6. Gruic-Sovulj, I., Dulic, M., Jaric, J., Cvetesic, N., Majsec, K., and Weygand-Durasevic, I. (2009) Efficiently activated serine analogue is not transferred to yeast tRNASer, Croatica Chem. Acta 83, 163-169.
  7. Lesjak, S., Boko, D., and Weygand-Durasevic, I. (2010) Seryl-tRNA synthetases from methanogenic archaea: suppression of bacterial amber mutation and heterologous toxicity, Food Technol. Biotechnol. 48, 512-518.
  8. Mocibob, M., Ivic, N., Bilokapic, S., Maier, T, Luic, M., Ban, N., and Weygand-Durasevic, I. (2010) Homologs of aminoacyl-tRNA synthetases acylate carrier proteins and provide a link between ribosomal and nonribosomal peptide synthesis, Proc. Natl. Acad. Sci. U.S.A. 107, 14585-14590.
  9. Weygand-Durasevic, I. and Ibba, M. (2010) New roles for codon usage, Science 329, 1473-1474.
  10. Godinic-Mikulcic, V., Jaric, J., Hausmann, C. D., Ibba, M. and Weygand-Durasevic, I. (2011) An archaeal tRNA-synthetase complex that enhances aminoacylation under extreme conditions, J. Biol. Chem. in press, doi: 10.1074/jbc.M110.168526.
  11. Mocibob, M., Ivic, N., Subasic, D., Luic, M. and Weygand-Durasevic, I. (2011) Substrate recognition by novel family of amino acid:[carrier protein] ligases, submitted


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