| Title: | Associate Professor |
| Location: | 231 |
| Public phone number: | +385 1 4606 134 |
| Internal phone number: | 6134 |
| E-mail: | |
| Department: | Division of Physical Chemistry |
undergraduate
graduate
Dr. Nikola Bregović is an Associate Professor at the Division of Physical Chemistry, Faculty of Science, University of Zagreb. He graduated from the Department of Chemistry, Faculty of Science, University of Zagreb in 2009. His research interests include supramolecular chemistry with primary focus on thermodynamics of anion binding, ion-pair complexation and cation coordination. He was included in numerous research projects as collaborator and has led several research projects. In the scope of the most recent, ongoing projects he is developing technologies for thermodynamic characterisation of various processes. Prof. Bregović is involved in teaching several courses including Electrochemistry, Physical Supramolecular Chemistry, Physico-Chemical Methods in Drug Studies, and Laboratory in Physical Chemistry. He has supervised one defended doctoral dissertation (Marija Cvetnić, PhD), several diploma theses, a student work awarded the Rector award, and is currently supervising two doctoral students. In 2013 Nikola was the Winner of the RSC Mpemba Competition and the same year he was awarded the Faculty of Science award for exceptional scientific achievements.
Show publications in CRORIS
1. Cvetnić, M., Cindro, N., Bregović, N. & Tomišić, V. Thermodynamics of Anion Binding by (Thio)ureido-calix[4]arene Derivatives in Acetonitrile. ACS Phys. Chem. Au (2024). doi:10.1021/acsphyschemau.4c00077
2. Cvetnić, M., Šplajt, R., Topić, E., Rubčić, M. & Bregović, N. Direct thermodynamic characterization of solid-state reactions by isothermal calorimetry. Phys. Chem. Chem. Phys. 26, 67–75 (2023).
3. Cvetnić, M., Cindro, N., Topić, E., Bregović, N. & Tomišić, V. Supramolecular Handshakes: Characterization of Urea-Carboxylate Interactions Within Calixarene Frameworks. Chempluschem 89, (2024).
4. Kumar, L. et al. Computational evaluation of halogen-bonded cocrystals enables prediction of their mechanochemical interconversion reactions. Chem. Sci. 14, 3140–3146 (2023).
5. Jasprica, I. et al. Utilization of a kinetic isotope effect to decrease decomposition of ceftriaxone in a mixture of D2O/H2O. Eur. J. Pharm. Sci. 187, (2023).
6. Radman, K. et al. Conformational change induced by binding of Mn2+ ions activates SloR transcription factor in Streptococcus mutans. Int. J. Biol. Macromol. 290, 138828 (2025).
7. Sokač, K. et al. Controlled release of dasatinib from cyclodextrin-based inclusion complexes by mechanochemistry: A computational and experimental study. Int. J. Pharm. 675, 125552 (2025).
8. Barišić, D., Tomišić, V. & Bregović, N. Acid-base properties of phosphoric and acetic acid in aprotic organic solvents – A complete thermodynamic characterisation. Anal. Chim. Acta 1046, 77–92 (2019).
9. Zhang, Y., Torker, S., Sigrist, M., Bregović, N. & Dydio, P. Binuclear Pd(I)-Pd(I) Catalysis Assisted by Iodide Ligands for Selective Hydroformylation of Alkenes and Alkynes. J. Am. Chem. Soc. 142, 18251–18265 (2020).
Development of calorimetric cell for characterization of mechanochemical reactions )NPOO.C3.2.R3-
I1.05.0409), PI: Assoc. Prof. Nikola Bregović
Development of a multireactor system for simultaneous conductometric and turbidimetric investigation of the dissolution ofactive pharmaceuticall ingredients, PI: Assoc. Prof. Nikola Bregović
Thermodynamic, spectroscopis, and structural aspects of calixarene coordiantion reactions (CalixCORE), PI: Prof Vladislav Tomišić
Coordination Reactions of Macrocyclic Ligands in Solution (MacroSol), PI: Prof Vladislav Tomišić
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