1. komponenta

Lecture type	Total
Lectures	30
Seminar	15

* Load is given in academic hour (1 academic hour = 45 minutes)

PRINCIPLES OF PHYSICAL-ORGANIC CHEMISTRY: Theoretical considerations, Isotope effects, Correlations of structure and reactivity, Solvent effects, Acids and bases, electrophiles and nucleophiles, Catalysis. SELECTED REACTION MECHANISMS: Substitution reactions at saturated carbon, Neighboring group participation, Elimination reactions, Polar addition reactions, Reactions of carbonyl group, Nucleophilic and electrophilic substitution at aromatic carbon, Pericyclic reactions.
EXPECTED COMPETENCES TO BE ACQUIRED:
Students will be able to
- explain the types and causes of isotope effects, and describe their usage in organic mechanisms analysis,
- explain the basic ideas behind the correlation between structure and reactivity,
- explain the solvent effects on organic reactions,
- deduce the relative stabilities of reactive intermediates and transition states,
- identify all most important types of organic reaction mechanisms,
- use tools of physical-organic chemistry to deduce details of organic reaction mechamisms.

1. Physical Organic Chemistry, N. S. Isaacs, Longman, London, 1995.
2. Physical and Mechanistic Organic Chemistry, R. A. Y. Jones, Cambridge University Press, Cambridge, 1984.
3. Advanced Organic Chemistry, Part A: Structure and Mechanisms, F. A. Carey i R. J. Sundberg, Kluwer Academic/Plenum Publishers, New York, 2000.
4. Modern Physical Organic Chemistry, E. V. Anslyn, D. A. Dougherty, University Science Books, 2006.

Izborni predmeti izvan odabranih grana - Regular study - Analytical and inorganic chemistry
Mandatory course - Regular study - Analytical and organic chemistry
Izborni predmeti izvan odabranih grana - Regular study - Analytical and physical chemistry
Izborni predmeti izvan odabranih grana - Regular study - Analytical chemistry and biochemistry
Mandatory course - Regular study - Biochemistry and organic chemistry
Izborni predmeti izvan odabranih grana - Regular study - Biochemistry and physical chemistry
Mandatory course - Regular study - Inorganic and organic chemistry
Izborni predmeti izvan odabranih grana - Regular study - Inorganic and physical chemistry
Izborni predmeti izvan odabranih grana - Regular study - Inorganic chemistry and biochemistry
Mandatory course - Regular study - Physical and organic chemistry

Izborni predmeti izvan odabranih grana - Regular study - Analytical and inorganic chemistry
Izborni predmeti izvan odabranih grana - Regular study - Analytical and physical chemistry
Izborni predmeti izvan odabranih grana - Regular study - Analytical chemistry and biochemistry
Izborni predmeti izvan odabranih grana - Regular study - Biochemistry and physical chemistry
Izborni predmeti izvan odabranih grana - Regular study - Inorganic and physical chemistry
Izborni predmeti izvan odabranih grana - Regular study - Inorganic chemistry and biochemistry