Course objectives:
The aim of the course Microbiology of Pathogens is to (i) familiarise students with the causative agents of the major infectious diseases of viral, bacterial and fungal aetiology; (ii) teach them about the mechanisms of pathogenesis of diseases caused by different groups of microbes; (iii) methods of laboratory detection and characterisation of microbial pathogens and (iv) methods of prevention and (v) therapeutic approaches in the treatment of diseases of microbial aetiology.
Thematic units of lectures:
1. Introductory lecture, introduction to the organization of the course (the rights and obligations of student)
2. From the theory of miasms to the etiological cause - 1st Part (plague of the 14th century as an example of the epidemic)
3. From the theory of miasms to the etiological cause - Part 2 (history, millestones, scientific approach as a paradigm)
4. Arheae, procariae and eucariae and infectious diseases
5. Terms in microbial pathogenesis, disease as a function of dynamic variables of host and microbes, systemic view on the disease
6. Epidemiological measures: Vograliks chain, prevention of infection
7. Measures of protection against infection. Part 1: active and passive immunization
8. Measures of protection against infection. Part 2: disinfectants and antiseptics, sterilization, causal medication
9. -14. The causes of disease - bacterial, fungal, viral and parasitic etiology: alimentary toxiinfections, poisoning, infections of the upper and lower respirstory system, infections of genito-urinary system, skin infections, infections of the CNS and others.
15. Human mcirobiome: Organization of epidemiology in the Croatia / EU, ECDC, EMA
Seminal topics:
1. Intracellular pathogens
2. Vectors of infectiouse diseases
3. Microbial pathogenesis of plague, Y. pestis
4. Modulation of skin microbiome
5. Differences archaea-prokariae, exo-Earth biology
6. Modulation of virulence of Candida albicans - a model for research
Exercises:
1. Microbiological control of air quality
2. Urine culture, identification of bacteria and antibiogram
3. stool examination on parasites
4. stool examination on salmonella
5. Identification of medically important yeasts, molds and dermatophytes
6. Wound swab on anaerobes, cultivation and identification (api)
7. trichina and artificial digestion
8. Microbiological testing of non-living environment on S. aureus, coliforms
9. Throat swab on BHSA
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Medicinska mikrobiologija, Kalenić S i sur., Medicinska naklada, Zagreb, 2014.
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Medical Microbiology, Murray i sur., Elsevier, 2020.
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Pristupačnost
