| Title: | Full Professor |
| Public phone number: | +385(0)1 4877 735 |
| Internal phone number: | 105 |
| E-mail: | |
| Department: | Division of Animal Physiology |
undergraduate
graduate
integrated undergraduate and graduate
doctoral
Predmet
Curriculum Vitae
PERSONAL INFORMATION
Name and surname
Nada Oršolić
Academic title
PhD
Year and institution
of PhD obtained
1999, Department of Animal Physiology, Faculty of Science, University of Zagreb
Address
Rooseveltov trg 6, HR-10000 Zagreb, Croatia
Phone
+385(1)4877 747; +385(1)4877 735
Fax
+385(1)4826 260
norsolic@yahoo.com; nada.orsolic@biol.pmf.hr
Citizenship
Croatian
Date and place of birth
January 31, 1960
WORK EXPERIENCE
Date (from – until)
26 May 1987 – today
Institution
Department of Animal Physiology, Faculty of Science, University of Zagreb
Position
Full Professor
Work field
Research in Cancer chemoprevention and chemotherapy, free radical biology and Cancer biochemistry, nutrition and cancer, flavonoids and anticancer drug design, Cancer immunology and cancer therapy with natural products, Natural products and diabetes, flavonoids as phytoestrogens in osteoporosis, Natural products and inflammation, Radioprotection with natural products, Cytotoxic and genotoxic effects of inhalation anesthetics, Anesthetics in combination with chemotherapy and radiotherapy,
Date (from – until)
2001-2002
Institution
MD Anderson Cancer Center (Department of Leukemia), Division of Cancer Medicine, Huston, Houston, Texas, U.S.A.
Position
Postdoctoral fellow
Work field
The possible mechanism of new antileucemic drug on parental and/or resistant cells of acute and chronic myelogenous leukemia in vitro and xenograf model in vivo.
Date (from – until)
…
Institution
Position
…
Work field
…
EDUCATION
Date
June 18, 1999
Place
Zagreb
Institution
Faculty of Science, University of Zagreb
Title of qualification awarded
PhD in Biology, Molecular Biology
Date
July 5, 1991
Place
Zagreb
Institution
Faculty of Science, University of Zagreb
Title of qualification awarded
MSc in biology, Molecular Biology
Date
April 24, 1984
Place
Zagreb
Institution
Faculty of Science, University of Zagreb
Title of qualification awarded
BSc in Biology, Biology with Ecology
Date
March 6, 1985
Place
Zagreb
Institution
Faculty of Science, University of Zagreb
Title of qualification awarded
BSc in Biology
LANGUAGES
mother tongue
Croatian
english language
speaking
B2
writing
B2
reading
B2
research and other projects
2010-2011 Project leader for in vivo research “In vivo study of NAVS very low-aromatic rich in steranes naphtalane” The survey was conducted for the company “MEDICOPHARMACIA”, d.o.o., Topniška 4, 1000 Ljubljana.
2007 - today: Project leader „Chemoprevention of tumor growth by polophenolic compounds“119-0000000-1255
2007 - today: Project leader Federal Ministry of Education and Science, Bosnia and Herzegovina
2007 - today: Project collaborator „Immunoadjuvant and protective effects of propolis in animals“ M
2001-2006: Project collaborator «Genetic markers in animal breeding»0048105. Dr. sc. Mirko Lojkić
1996 - 2002:Project collaborator M
1991-1995 Project collaborator ”Experimental Hematology: differentiation and turnover of blood cells” The ministry of Science, Education and Sports Republic of Croatia No. Project: 1-08-304. Project leader: Prof. Dušan Volf
TEACHING
Undergraduate study:
Lecturer: Animal Physiology, Experimental animals in biological research
Integrated undergraduate and graduate studies
Lecturer: Imunology, Tumor Biology
Graduate study:
Lecturer: Immunology, Immunology and immunogenetics, Comparative Immunology, Methods in immunology, General oncology, Immunobiology of tumor and metastasis, Tumor biology, Physiology of oxidative stress in Human and Animals, Physiological mechanism in Toxicology, Ecological Immunology, Human Physiology.
Postgraduate study:
Lecturer: Chemoprevention and biotherapy of tumor, Mutagenes and antimutagens, Animal models in rodents in experimental oncology
MENTORSHIPS OF DOCTORAL AND MASTER DISSERTATIONS AND TRAINING OF YOUNG RESEARCHERS AND SCIENTISTS
Supervisor of Bachelor's degree works – 25; Supervisor for the Rectors Prize – 7; Supervisor or Co-supervisor of Final master works – 177; Supervisor of Final master science thesis (Master Dissertations) – 6; Supervisor of Final PhD thesis (Doctoral Dissertations) - 15
AWARDS AND RECOGNITIONS
Beekeeping Society of Zagreb (bronze bees)-December 6th, 2006
MEMBERSHIP IN SCIENCE ORGANIZATIONS AND BODIES
Team leader and coordinator of education at the Department of Animal Physiology, 1997-2001; Head of laboratory facilities for breeding of animals at the Department of Animal Physiology 1999-2005 and from 2007-2013; Team leader and coordinator of education at the Department of Animal Physiology, 2002-2009; Member of the admission procedure at the Biology Department from 2002-2008; Member of the organizing committee for graduate studies at the Bologna Process; Student leader for direction of a professor of biology from 2003-2009; Head of Department of Animal Physiology from 2007-2013
COMMISSIONS, COMMITTEES, BOARDS AND WORK GROUPS
Croatian Biological Society; Croatian Immunological Society; Croatian Physiological Society; Croatian Society for Animal Science – CROLASA; 2008. Member of the Editorial Board for the journal-Journal of ApiProduct and ApiMedical Science (JAAS); 2010. Member of the Editorial Board of the journal- Bioinfo Publications; 2013 Member of the Editorial Board of the journal -Advances in Bioscience and Clinical Medicine (ABCmed)
PAPERS
CC scientific papers: 59; Other scientific papers: 65, 80 domestic and 85 international meeting abstracts
Total number of publications: 84 (WOS)
Total number of citations: 867 (WOS)
H-index: 18 (Web of Science)
Total number of publications: 75 (SCOPUS)
Total number of citations: 905 (SCOPUS)
H-index: 18 (SCOPUS)
OTHER RESEARCH ACTIVITIES
Reviewer -171 papers (see Attachment: N. Oršolić-Report on the scientific and professional activities)
COMPUTER SKILLS
Proficient in MS Office software package, good working knowledge of Adobe Reader, Photoshop and Illustrator, including internet electronic communication, good working knowledge of SAS programme for statistical analysis
OTHER IMPORTANT SKILLS AND COMPETENCES
In vivo studies: Can handle experimental animals like Rats, Mice, Insects, Birds, Frogs; intraperitoneal and subcutaneous injection; Dissection and excision of various organs.
Protein Biochemistry: Western Blotting Analysis; ELISA, Separation and purification of proteins
Cell Biology: General maintenance of cell lines; Proliferation and toxicity studies using Tritiated thymidine incorporation assay, MTS assay, clonogenic assay; micronucleus test in vitro and in vivo; Apoptosis and necrosis assay methods - Staining techniques (Propidium Iodide, AnnexinV, and Fluorescence actin staining, TUNEL TASC™ enzymatic labeling assay, DNA gel electroforesis); Determination of functional activity of macrophages, NK-cells T-and B- cells
Molecular Biology: Genomic DNA extraction; PCR, spectrophotometric assay, comet assay
ADDITIONAL INFORMATION AND NOTES
List of publications, Supervisors, Reviewers and other scientific activities, giving a separate attachment:
Attachment: N. Oršolić-Report on the scientific and professional activities
Note: this list of papers is located in an maintained by the Ruđer Bošković Institute which is in charge of the Croatian Scientific Bibliography Database (CROSBI). This link will take you to the appropriate CROSBI page of this person, containing a list of papers they have themselves entered in the database.
Oršolić N, Goluža E, Đikić D, Lisičić D, Sašilo K, Rođak E, Jeleč Ž, Vihnanek Lazarus M, Orct T. (2014) Role of flavonoids on oxidative stress and mineral contents in the retinoic acid-induced bone loss model of rat" European Journal of Nutrition 53(5):1217-27.
Oršolić N, Skurić J, Đikić Đ, Stanić G. (2014) Inhibitory effect of a propolis on Di-n-Propyl Disulfide or n-Hexyl salicilate-induced skin irritation, oxidative stress and inflammatory responses in mice. Fitoterapia 93:18-30.
Orsolic N, Car N.(2014) Quercetin and hyperthermia modulate cisplatin-induced DNA damage in tumor and normal tissues in vivo. Tumor Biology 35(7):6445-54.
Oršolić N. (2013) Possible Molecular Targets of Bee Venom in the Treatment of Cancer: Application and Perspectives. Forum on Immunopathological Diseases and Therapeutics, 4(3–4):275–315.
Oršolić N. ( 2012) Bee venom in cancer therapy. Cancer Metastasis Rev. 31(1): 173-194.
Oršolić N, Gajski G, Garaj-Vrhovac V, Dikić D, Prskalo ZŠ, Sirovina D. (2011) DNA-protective effects of quercetin or naringenin in alloxan-induced diabetic mice. Eur J Pharmacol. 656(1-3):110-8.
Oršolić N (2010). A review of propolis antitumor action in vivo and in vitro. Journal of ApiProduct and ApiMedical Science 2(1): 1-20.
Orsolic N. (2009). Bee honey and cancer. Journal of ApiProduct and ApiMedical Science 1 (4): 93 – 103.
Scientific evidence of the use of propolis in ehtnomedicine” (Editors: Oršolić N. and Bašić I). Ethnopharmacology- Review Book, Transworld Research Network, India, 2008.
Oršolić N. and Bašić I. (2007) Cancer chemoprevention by propolis and its polyphenolic compounds in experimental animals. Phytochemistry and Pharmacology III, (Editors: V. K. Singh, J. N. Govil & C. Arunachalam, STUDIUM PRESS, LLC, U.S.A). Recent Progress in Medicinal Plants 17: 55-113.
Orsolic N, Golemovic M, Quintas-Cardama A, Scappini B, Manshouri T, Chandra J, Basic I, Giles F, Kantarjian H, Verstovsek S. (2006) Adaphostin has significant and selective activity against chronic and acute myeloid leukemia cells.Cancer Sci. 97(9):952-60.
Oršolić N, Giles FJ, Gourdeau H, Golemović M, Beran M, Cortes J, Freireich EJ, Kantarjian H, Verstovšek S. (2004). Troxacitabine and imatinib mesylate combination therapy of chronic myeloid leukemia:preclinical evaluation. Br. J. Haematol. 124:727-738.
Oršolić N. and Bašić I. (2003) Immunomodulation by water-soluble derivative of propolis (WSDP) a factor of antitumor reactivity. J. Ethnopharmacol. 84: 265-273.
Pristupačnost
