1. komponenta

Lecture type	Total
Lectures	60
Seminar	15

* Load is given in academic hour (1 academic hour = 45 minutes)

COURSE CONTENT:
1. Elimination reactions
1.1. Mechanisms and stereochemistry of elimination reactions
1.2. Elimination versus substitution
2. Electrophilic additions to unsaturated carbon
2.1. Mechanisms and stereochemistry of addition reactions
2.2. Addition to conjugated dienes and conjugated carbonyl compounds
2.3. Homogenic and heterogenic catalysis
3. Pericyclic reactions
3.1. (4 + 2) cycloaddition and dipolar cycloaddition
3.2. Orbital symetry control of pericyclic reactions (HOMO-LUMO and correlation
diagram methods)
3.3. Electrocyclic reactions and sigmatropic rearrangements
4. Electrophilic aromatic substitutions
4.1.Aromatic and antiaromatic compounds
4.2. Mechanism of electrophilic aromatic substitution
4.3. Substituent effects on orientation in electrophilic aromatic substitution
4.4. Reactions of heteroaromatic compounds
5. Nucleophilic aromatic substitution
6. Molecular rearrangements
7. Free radical reactions
8. Organic synthesis
8.1. Design of a synthesis (starting materials, construction reactions, functional group
interconvesions and protecting groups)
8.2. Retro-synthetic approach
9. Natural organic compounds
9.1. Carbohydrates
9.2. Amino acids and proteins
9.3. Lipids
9.4. Alkaloids
9.5. Pheromones

LEARNING OUTCOMES:
After completion of this course, the successful student will be able to:
- represent organic molecules in space using structural formulae and give them names using IUPAC nomenclature
- write and explain the mechanisms of elimination reactions, electrophilic additions on unsaturated and conjugated substrates, pericyclic reactions and electrophilic and nucleophilic aromatic substitution
- explain the influence of structure on reactivity of organic molecules
- define aromaticity and antiaromaticity and explaine on examples
- plan a multistep synthesis of simple organic compounds on the basis of acquired knowledge in organic chemistry
- connect structure of biologically important molecules with their biological role

Enrollment :
Passed : Physical Chemistry 1
Attended : Organic Chemistry 1
Attended : Physical Chemistry 2

Examination :
Passed : Organic Chemistry 1

Mandatory course - Regular study - Biology and Chemistry Education