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Load:
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1. komponenta
| Lecture type | Total |
| Lectures |
20 |
| Seminar |
10 |
* Load is given in academic hour (1 academic hour = 45 minutes)
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Description:
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The signal and noise. Spectroscopy in time and frequency domain. Fourier transformation (FT) and spectroscopy. Interferometry and FT in infrared spectroscopy (IR). Dispersive and FT Raman spectroscopy. Near IR spectroscopy (NIR). Two-dimensional IR spectroscopy. Time-resolved vibrational spectroscopy (rapid scan and step scan). Pulse nuclear magnetic resonance (NMR) techniques. FT in NMR; two- and multidimensional techniques. NMR parameters (chemical shifts, couplings, relaxation times) and molecular structure. NMR and conformational analysis. Molecular interactions studied by NMR and drug design. Mass spectrometry (MS). Mass analysers; sector, quadrupol, ion cyclotron resonance and FT (FT ICR), time of flight (TOF). Ionization methods; electron impact (EI), chemical ionization (CI), fast atom bombardment (FAB), laser desorption ionization (LDI), matrix assisted laser desorption ionization (MALDI), electrospray ionization (ESI). Tandem MS (MS/MS, MSn). Spectra interpretation. Mechanisms of fragmentation. Analysis of complex mixtures by using hyphenated techniques GC-MS, LC-MS, LC-NMR etc.description of instruction methods Lectures, seminars, demonstrations, consultations
description of course/module requirements Written and/or oral exam
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Literature:
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- OBVEZNA LITERATURA:
B. Schrader (Ed.), Infrared and Raman Spectroscopy. Methods and Applications, VCH, Weinheim, 1995.
I.R. Lewis, H.G.M. Edwards (Eds.), Handbook of Raman Spectroscopy, Marcel Dekker, New York 2002.
H. Fribolin, Basic One- and Two-Dimensional NMR Spectroscopy, VCH, Weinheim 2005.
T.D.W. Claridge, High-Resolution NMR Techniques in Organic Chemistry, Pergamon, Amsterdam 2009.
J. H. Gross: Mass Spectrometry, Springer-Verlag Berlin Heidelberg, 2011.
- DOPUNSKA LITERATURA:
Suvremeni opsežniji revijski članci i znanstvene monografije
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Pristupačnost
